Comparative Genomic Analysis of Arctic Permafrost Bacterium Nesterenkonia sp. PF2B19 to Gain Insights into Its Cold Adaptation Tactic and Diverse Biotechnological Potential

Nesterenkonia sp. PF2B19, a psychrophile was isolated from 44,800-year-old permafrost soil. This is the first report on comparative genomics of Arctic. Genome PF2B19 exhibited presence vast array genetic determinants involved in cold adaptation i.e., response to cold-associated general, osmotic, and oxidative stress. These genomic attributes proved be valuable unraveling adaptive tactics employed by for survival soils Genomic analysis has given some insight into biotechnological potential this strain, particularly as source cold-active enzymes, bioremediating agent plant growth-promoting bacteria.